I thought I read/heard that this is now available by injection as well as infusion is that true?
I have rituxin by injection in my abdomen. Saves me an hour and a half on infusion days. Burns going in.
I have just finished 6 months infusion of Retuximab. Yes, Monoclonal Antibodies and I was highly allergic to it so infused it over 27 hours after being hospitalized. My doctor and I had the conversation about oral or injection, NO, Rituxan must be given directly into the bloodstream in order for it to be effective. So instead of being taken as a pill or an injection, it is given as an infusion, which is a needle placed in a vein. For most people, over 4-8 hours. Infusions are given by trained healthcare professionals in outpatient if you tolerate it well. I did not so he had to hospitalize me. I got the Bendamustine, then Retuximab, then another dose of Bendamustine, then an injection of Neulasta. It is common for you to be given acetaminophen (Tylenol®), and diphenhydramine HCI (Benadryl®) before the Rituximab to reduce side- effects. One is spiking a high fever, the other is hives and blisters, like an allergy, which I had, twice. Also rigors. The doc said there is a chance that you will experience an allergic reaction to Rituximab of some sort. I still reacted to it, even with the Tylenol and Benadryl. I had anaphylactic reactions twice when they tried to run it ar a normal rate. So less reaction running it in slowly.
I'm allergic though to many things year round, not just seasonal allergies. 🤧🤒😷 I'm glad I went that route, the Lymphoma tumors are shrinking. 👏🏼👏🏼👏🏼👏🏼
Exactly the type of information I was seeking. Thanks so much for sharing.
That was quite a treatment you had to endure - especially with your allergic reactions. So glad that you are done. What is next for you?
I don't remember the specific drugs in the RCHOP they recommended for me at first - I remember that it included Rituximab and multiple others - once a month for 6 months I think. Then Moffit changed their rec to just Rituximab - once a week for 4 weeks. I was reeling from the bills at this point so I asked about the cost. It took so many calls to Dr, business office and ins and over a week to get an answer. Just another one of those things that I don't understand.
I finally got a very official legal document that showed that the center would bill something in the neighborhood of $50K for each treatment. My responsibility was $450/tx and there would be an extra cost of $150/shot for whatever drug - don't recall the name - if my white cell count dropped. I asked about the drug for the cell count drop and the nurse told me not to worry about it - because most people did not need it. I thanked her for the information and said I would not have known about it because it had never been mentioned. I asked about driving myself to/from treatment (it is maybe an hour drive for me). She said unlikely but definitely not for the first time because the benadryl they give you causes sleepiness. They needed to determine how I reacted to everything. That had never been mentioned either. You mentioned Tylenol - never mentioned. This kinda stuff drives me nuts - I don't like surprises. I had no idea it was an infusion either. Is this the norm, they tell you next to nothing and you just jump right in?
They gave me drug printouts back in Dec when this was first presented and I was pretty sick then but other than some possible side effects and info on contacts if you have certain side effects kind of thing, there was nothing else. I live alone so I try to be as prepared as possible.
Thanks so much for the input. I knew I read it somewhere.
I googled it out of curiosity and this is what I found (I cut and paste) ... Rituximab injection (Rituxan) is used to treat pemphigus vulgaris (a condition that causes painful blisters on the skin and the lining the mouth, nose, throat and genitals). Rituximab injection products are in a class of medications called monoclonal antibodies.
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