Jay, I was allergic first treatment with rash. But on later treatments gave me Benadryl with Rituxan and did great! I always felt good ready to go eat and shop. Even after Rituxan and low dose chemo never felt sick.
I notice mild numbness in toes from it, but hey it's worth being well now! Good luck!

Good Luck🥰 I hope you get the treatment. I had all the same symptoms but had Rituxan for the same diagnosis. The night sweats are the worst. I didnt wait for treatment. I started right after being diagnosed. Lethargy is hard to deal with as it comes and goes. I had good days mixed in with bad but more bad.

Thank you. I have had five treatments now. Legs hurt during treatments and extremely tired after but otherwise good. I have had additional scans and lymph nodes are smaller. My Doctor placed me on a two year maintenance plan. I take a treatment every two months.

Hi Jay, I received Rituxan once a week for 5 weeks. I have MS so my symptoms are probably more severe than any you would have. During the first treatment I had a slight slight headache, got cold and just a little bit nauseous. That was treated immediately by the nurse. They stopped the treatment, administered?? and after about 30 minutes all symptoms were gone and they started the infusion again at a slower rate and increased in steps and no further symptoms. At the car my legs were extremely weak. Needed help getting into the car. As my legs are normally weak, the severe weakness, I attribute to the MS. Second time some weakness but not as bad and remaining treatments no symptoms. I received Rituxan only and not R-CHOP therapy. First infusion symptoms were normal and nurses were checking on me about every 5 minutes. Symptoms started around one hour after infusion was started. Symptoms are normal and mine were very weak. Good luck. Hugs. I had radiation for 25 days and will have a PETCT scan 3 months after final treatment. Either treatment the scan was 3 months after.

I had a severe back spasm reaction to rituxan my second treatment. Third one my muscles and joints were screaming for a few days,so I no longer take it.Some people like me do have bad reactions to it,but most are able to handle it