Waldenstrom's macroglobulinemia (WM), also called lymphoplasmacytic lymphoma, is a slow-growing form of non-Hodgkin lymphoma that affects B cells in your immune system. It typically develops in the bone marrow, where cancer cells multiply and can decrease levels of normal blood cells.
The cancer cells produce an abnormal Show Full Answer
Waldenstrom's macroglobulinemia (WM), also called lymphoplasmacytic lymphoma, is a slow-growing form of non-Hodgkin lymphoma that affects B cells in your immune system. It typically develops in the bone marrow, where cancer cells multiply and can decrease levels of normal blood cells.
The cancer cells produce an abnormal protein called macroglobulin (M protein), which can build up in both organs and lymph nodes. This can lead to blood thickening (hyperviscosity). Common symptoms may include fatigue, nosebleeds, headaches, dizziness, and pain. Some MyLymphomaTeam members report experiencing bone and joint pain, digestive issues, bruising, and skin changes. The condition is often diagnosed through blood tests and bone marrow biopsy.
Treatment options include chemotherapy, immunotherapy, radiation therapy, targeted drugs, and stem cell transplants. Some patients may undergo plasmapheresis to filter excess proteins from the blood and reduce symptoms. While WM progresses slowly, many people can manage their symptoms with appropriate treatment.
February 23, 2025
Continue with Facebook
Continue with Email
Join
Your Privacy Choices
