I was treated with bendamustine and rituximab and never had itching or a rash. Of course, that is just my reaction and I was lucky.
November 14, 2025
Can bendamustine and rituximab cause excessive itching?
Yes, rituximab can cause an itchy rash as part of an allergic reaction or sensitivity to the medication. This is a known side effect that some people experience during treatment.
Itching with lymphoma can also occur due to the lymphoma itself, as your immune system Show Full Answer
Can bendamustine and rituximab cause excessive itching?
Yes, rituximab can cause an itchy rash as part of an allergic reaction or sensitivity to the medication. This is a known side effect that some people experience during treatment.
Itching with lymphoma can also occur due to the lymphoma itself, as your immune system releases chemicals that irritate the skin. This type of itching often gets worse when it's hot or at night when you're trying to sleep.
If you're experiencing excessive itching during treatment, it's important to let your healthcare team know. They can help determine whether it's related to the medication or the lymphoma itself, and suggest ways to manage it.
Some strategies that may help include:
* Avoiding scratching
* Keeping fingernails trimmed
* Using moisturizer regularly
* Taking oatmeal baths
* Applying cool compresses
* Wearing soft, loose-fitting clothes
* Using fragrance-free soaps and products
Your doctor may also be able to adjust your treatment or prescribe medications to help control the itching.
November 10, 2025