Do people experience severe leg and body cramps after treatment for aggressive B-cell non-Hodgkin lymphoma, and what helps?
Yes, leg and body pain after treatment is something other members have experienced. A MyLymphomaTeam member asked about leg and bone pain five years after chemo, noting it was getting worse. Another Show Full Answer
Do people experience severe leg and body cramps after treatment for aggressive B-cell non-Hodgkin lymphoma, and what helps?
Yes, leg and body pain after treatment is something other members have experienced. A MyLymphomaTeam member asked about leg and bone pain five years after chemo, noting it was getting worse. Another member shared they still wake up with bone pain even eight weeks after finishing their final chemotherapy round.
The experiences vary quite a bit:
- Some members report bone pain that "comes and goes" years after treatment
- Others experience it occasionally even after being in remission for a year or more
- The pain can persist for several years post-treatment
Some members found relief by talking to their healthcare team about adjusting medications. For example, members who experienced severe leg and back pain from certain medications like Neulasta were able to switch to alternatives like Zarxio or Neupogen, which caused less severe pain.
It's important to tell your healthcare team about these symptoms. They may be able to adjust dosages or switch you to different medications that cause less discomfort. Your care team can also help you manage these side effects with other supportive treatments.
December 18, 2025
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