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January 31
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Can primary cutaneous marginal zone B-cell lymphoma be considered cured after complete excision with clear margins?

Currently, marginal zone lymphomas, including the cutaneous type, cannot be considered cured. While complete surgical removal with clear margins is an effective treatment option, there's an important Show Full Answer

Can primary cutaneous marginal zone B-cell lymphoma be considered cured after complete excision with clear margins?

Currently, marginal zone lymphomas, including the cutaneous type, cannot be considered cured. While complete surgical removal with clear margins is an effective treatment option, there's an important consideration to keep in mind.

About 50 percent of people with cutaneous B-cell lymphoma experience a recurrence of tumors after surgery. This means that even with successful excision, the lymphoma can return over time.

That said, the prognosis for cutaneous B-cell lymphoma is generally positive. The five-year overall survival rate for most subtypes is greater than 90 percent, which is encouraging.

After surgical removal, regular monitoring is recommended to watch for any return of symptoms. This ongoing surveillance is important because the lymphoma tends to relapse, even after successful initial treatment.

While you can't consider it "cured" in the traditional sense, many people live well for years after treatment. It's best to discuss your specific situation and long-term outlook with your healthcare team, as they can provide personalized guidance based on your individual case.

January 31

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