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Real members of MyLymphomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
March 24
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A MyLymphomaTeam Member

Yes that’s a big jump. You’ll need to ask your specialist about that. Fo you have any aggressive markers?

April 3
A MyLymphomaTeam Member

Honestly I don't know. I sent her the bloodwork showing the jump and she said I am fine. I feel like I get more information talking to you than I do my oncologist. But maybe her nurse lied and said she showed her the blood report from the ER and didn't. I am conflicted because the oncologist is amazing but the place/other staff I am not very happy with. What is an aggressive marker?

April 3
MyLymphomaTeam

Does an 83% increase in lymphocytes over 2 months mean anything for small lymphocytic lymphoma (SLL)?

Yes, this increase could be significant. How quickly lymphocytes grow is an important factor in understanding SLL progression. If lymphocyte counts double in less than a year, it often signals more aggressive disease and Show Full Answer

Does an 83% increase in lymphocytes over 2 months mean anything for small lymphocytic lymphoma (SLL)?

Yes, this increase could be significant. How quickly lymphocytes grow is an important factor in understanding SLL progression. If lymphocyte counts double in less than a year, it often signals more aggressive disease and may indicate a worse prognosis.

Your current count of 5.92 (likely 5,920 per microliter) is just above the threshold that distinguishes SLL from chronic lymphocytic leukemia (CLL). When the absolute lymphocyte count is 5,000 or more, it's typically classified as CLL rather than SLL, though they're treated very similarly.

An 83% increase in just 2 months represents rapid growth. Rapidly rising lymphocyte levels can be a sign that the disease is becoming more active. This is something your doctor will want to monitor closely, as it may influence treatment decisions.

Your healthcare team will likely consider this alongside other factors like:
- Your overall health and symptoms
- Stage of disease
- Specific gene changes in your cancer cells
- Levels of proteins like beta-2 microglobulin

It's important to discuss these results with your oncologist, who can interpret them in the context of your complete medical picture and determine if any changes to your treatment plan are needed.

March 24

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