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Real members of MyLymphomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyLymphomaTeam Member asked a question πŸ’­
5 hours ago
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A MyLymphomaTeam Member

No, I meant O-CHOP. I went through a rough infusion of Rituximab with many different kinds of reactions before finally being determined to be allergic to it by doctors at Moffitt Cancer center. They started O-CHOP and I've just completed 6 rounds. I was wondering if results are similar to R-CHOP.

5 hours ago
MyLymphomaTeam

It sounds like you might be referring to R-CHOP, which is the standard first-line treatment for Diffuse Large B-Cell Lymphoma (DLBCL). The "O" in CHOP actually stands for Vincristine, which was formerly sold under the brand name Oncovin β€” that's likely where the confusion comes in!

R-CHOP is a combination of five drugs:

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It sounds like you might be referring to R-CHOP, which is the standard first-line treatment for Diffuse Large B-Cell Lymphoma (DLBCL). The "O" in CHOP actually stands for Vincristine, which was formerly sold under the brand name Oncovin β€” that's likely where the confusion comes in!

R-CHOP is a combination of five drugs:

- R β€” Rituximab, an immunotherapy that helps the immune system target cancer cells
- C β€” Cyclophosphamide, a chemo drug that damages cancer cell DNA
- H β€” Doxorubicin, a chemo drug that kills cancer cells
- O β€” Vincristine (formerly Oncovin), which interferes with cancer cell growth
- P β€” Prednisone, a steroid that reduces inflammation and helps kill cancer cells

Most of these are given through an IV, except Prednisone, which is taken as a pill. Treatment typically involves six cycles, each lasting 21 days, though the number of cycles can vary depending on the stage of lymphoma. R-CHOP has been shown to cure roughly 60–70% of newly diagnosed DLBCL cases.

It's always best to speak with a doctor about which treatment plan is right for your specific situation.

5 hours ago

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