Leukeran (Chlorambucil) for Lymphoma | MyLymphomaTeam

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Leukeran is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat Hodgkin lymphoma, chronic lymphocytic leukemia (CLL), lymphosarcoma, and giant follicular lymphoma. Leukeran is often used as part of a chemotherapy regimen. Leukeran is also known by its drug name, chlorambucil.

Leukeran is an anticancer drug and a member of a class of drugs called alkylating agents. Leukeran is believed to work by preventing the production of DNA in cells, thereby blocking cell division.

How do I take it?
Leukeran is taken daily by mouth.

Leukeran is available as a tablet.

Side effects
The FDA-approved label for Leukeran lists common side effects including nausea, vomiting, hair loss, tremors, confusion, itching, and mouth sores. Myelosuppression – decreased bone marrow activity that causes a dangerous drop in blood cell counts – is a common and dangerous side effect of taking Leukeran that may be permanent.

Rare but serious side effects listed for Leukeran include lung and liver damage, fetal harm in pregnant women, infertility in men and women, an increased risk for developing other cancers, and the potentially fatal skin reactions known as Stevens-Johnson syndrome and toxic epidermal necrolysis.

For more details about this treatment, visit:

Leukeran — RxList

Leukeran — Chemocare

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