| The Oncovin brand name has been discontinued in the U.S. for reasons unrelated to safety or efficacy. Other brand names or generic alternatives may be available. If you’re currently taking this medication, talk to your healthcare provider about safe options for transitioning to a different treatment. |
Overview
Oncovin is a prescription medication used to treat several types of cancer including Hodgkin lymphoma, non-Hodgkin lymphoma, multiple myeloma, and chronic leukemias. Oncovin is often combined with other drugs in chemotherapy regimens. Along with cyclophosphamide, doxorubicin, and the corticosteroid prednisone, Oncovin was part of the CHOP regimen, one of the most commonly used for non-Hodgkin lymphoma. Oncovin was also part of the seven-drug BEACOPP regimen for Hodgkin lymphoma. Oncovin was also known by its drug name, vincristine.
Oncovin was an anticancer drug used in chemotherapy. Oncovin was a member of a class of drugs called plant alkaloids. Oncovin was believed to work by interfering with the structure of cancer cells.
How was it taken?
Oncovin was administered as an intravenous infusion during chemotherapy treatment.
Side effects
The FDA-approved label for Oncovin listed common side effects including hair loss, mouth sores, nausea, diarrhea, vomiting, constipation, loss of appetite, abdominal pain, changes in the sense of taste, peripheral neuropathy (tingling or numbness in the extremities), urinary retention, and low blood cell counts. If Oncovin leaked into the skin or tissue at the injection site (a situation known as extravasation), it caused a painful inflammatory reaction.
Rare but serious side effects listed for Oncovin included fetal harm in pregnant individuals.
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