Splenic Marginal Zone Lymphoma (SMZL) does not typically cause bone pain directly. However, if SMZL spreads to the bone marrow, it can affect blood cell production, potentially leading to symptoms like fatigue or anemia. Bone pain is more commonly associated with other lymphoma subtypes, such as Primary Lymphoma of Bone. If Show Full Answer
Yes, it does. As I understand it, SMZL very often moves into the bone marrow. I have read that even removing the spleen (if it ever comes to that) does not "cure" the lymphoma because of bone marrow infiltration.
Bone marrow biopsy is how I was diagnosed so does that mean it's already in my bones