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Real members of MyLymphomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

I have one only very small spot show up n my PET scan and I’m not sure if I should try to have it biopsied or wait it out to see if it grows. I completed 6 rounds of pola r chp as I have stage 4 level 2 ipi for dlbcl nh. All other cancer cells are non existent according to my scan results. Any insight or advice would be kindly appreciated. Thank you.

August 31, 2025
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A MyLymphomaTeam Member

What did your oncologist recommend?

September 2, 2025
A MyLymphomaTeam Member

I would say get the biopsy better to be safe than sorry. I would much rather have something that I didn’t need then wish I did have something. I hope that helps

September 2, 2025
MyLymphomaTeam

PET scans work by showing areas where glucose (sugar) is being heavily consumed in the body, since cancer cells typically require high levels of sugar to grow. While these scans are helpful in detecting lymphoma, small spots can sometimes be challenging to definitively diagnose without additional testing.

A radiologist Show Full Answer

PET scans work by showing areas where glucose (sugar) is being heavily consumed in the body, since cancer cells typically require high levels of sugar to grow. While these scans are helpful in detecting lymphoma, small spots can sometimes be challenging to definitively diagnose without additional testing.

A radiologist interprets these images and communicates findings to your doctor, who can then determine if further investigation like a biopsy is needed. The fact that all other cancer cells are non-existent on your scan is a positive sign. It's completely normal to feel anxious about scan results. Many MyLymphomaTeam members share similar concerns about waiting for definitive answers. While this response can't provide medical advice about whether to biopsy or wait, this is an important discussion to have with your healthcare team who can evaluate your full medical history and specific situation.

August 31, 2025
A MyLymphomaTeam Member

Pops. I also had NHL DLBCL, stage 1S is primary spleen with 3.5 inch mass in my spleen. No evidence of lymphoma anywhere on 2 PET scans. But on a 6 months CT scan, this nodule.

September 29, 2025
A MyLymphomaTeam Member

7mm nodule, possible residual spleen from splenectomy. Watch and wait. That was my advice. 11 months cancer free when this happened. 6 months has passed well in 10 more days so ....

September 29, 2025

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