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Real members of MyLymphomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
October 28, 2025
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A MyLymphomaTeam Member

@A MyLymphomaTeam Member
Hey Renee, for sure report your symptom to your oncology team… They may want to do a bone biopsy to make sure it hasn’t progressed. Knowledge is Power and it’s good to know what is going on!! I’m also Stage 3 FL on W&W and my doctor wants me to call with anything new! Take care 🙏😊

October 28, 2025
MyLymphomaTeam

Could leg pain in Stage III follicular lymphoma on watch and wait be bone marrow related?

Yes, leg pain could potentially be related to bone marrow involvement. Between 40 to 70 percent of people with follicular lymphoma have cancer cells in their bone marrow, which can cause various symptoms.

When follicular lymphoma Show Full Answer

Could leg pain in Stage III follicular lymphoma on watch and wait be bone marrow related?

Yes, leg pain could potentially be related to bone marrow involvement. Between 40 to 70 percent of people with follicular lymphoma have cancer cells in their bone marrow, which can cause various symptoms.

When follicular lymphoma affects the bone marrow, it can lead to:
- Anemia (low red blood cells), causing fatigue
- Thrombocytopenia (low platelets), leading to easy bruising or bleeding
- Increased infections due to low white blood cells
- Bone pain

It's important to discuss this new symptom with your oncology team. They may want to check your blood counts or do other tests to determine if the lymphoma is affecting your bone marrow or if there's another cause for your leg pain.

Since you're on watch and wait, any new or worsening symptoms should be reported promptly, as they could indicate disease progression that might need treatment.

October 28, 2025

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