MyLymphomaTeam

Have you been offered CAR T-cell therapy for your lymphoma?

CAR T-cell therapy is typically offered to people with large B-cell lymphomas when the cancer has come back after treatment or hasn't responded well to earlier care. Many people who receive this therapy have already tried chemotherapy, targeted drugs, or even a Show Full Answer

Have you been offered CAR T-cell therapy for your lymphoma?

CAR T-cell therapy is typically offered to people with large B-cell lymphomas when the cancer has come back after treatment or hasn't responded well to earlier care. Many people who receive this therapy have already tried chemotherapy, targeted drugs, or even a stem cell transplant but still need another option.

Your care team will evaluate whether you're a good candidate based on:
- Your overall health and ability to handle the infusion and recovery period
- How your lymphoma has progressed over time
- Whether CAR T-cell therapy offers the best chance to control your disease

It may also be considered if you have fast-growing lymphoma or can't receive more intensive treatment options. There are currently three FDA-approved CAR T-cell therapies for large B-cell lymphoma:

- Axicabtagene ciloleucel (Yescarta) - approved for certain large B-cell lymphomas that haven't responded to at least two earlier treatments, or for some people whose lymphoma doesn't respond to first-line treatment or returns within 12 months

- Lisocabtagene maraleucel (Breyanzi) - approved for relapsed or refractory large B-cell lymphoma after at least two earlier treatments, or for some people whose lymphoma doesn't respond to first-line treatment or returns within 12 months

- Tisagenlecleucel (Kymriah) - approved for adults with relapsed or refractory large B-cell lymphomas who have already received two or more previous treatments

If you're considering this option, your care team can help determine which therapy might be right for your specific situation.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

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