Thank you very much for this information we have a scheduled meeting with a cart cell specialist at moffit later this month
April 4
Why would someone in remission be considered for CAR T-cell therapy after chemotherapy?
CAR T-cell therapy is typically used when lymphoma has relapsed (come back after treatment) or is refractory (didn't respond to treatment). However, newer guidelines allow it to be used earlier in some cases.
If someone's lymphoma Show Full Answer
Why would someone in remission be considered for CAR T-cell therapy after chemotherapy?
CAR T-cell therapy is typically used when lymphoma has relapsed (come back after treatment) or is refractory (didn't respond to treatment). However, newer guidelines allow it to be used earlier in some cases.
If someone's lymphoma didn't respond well to first-line chemotherapy or came back within 12 months after treatment, they may be eligible for CAR T-cell therapy even if they're currently in remission. This is because the therapy can help prevent the cancer from returning.
Some FDA-approved CAR T-cell therapies are now approved as second-line treatment for people whose lymphoma:
- Didn't respond to initial chemotherapy
- Relapsed within a year of finishing treatment
The goal is to use CAR T cells while the person is doing better, rather than waiting until the lymphoma becomes harder to control. This approach can lead to longer-lasting remissions.
It's worth discussing with the healthcare team why this treatment is being recommended in this specific situation, as they'll consider the individual's response to chemotherapy and risk of relapse.
April 3
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