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Real members of MyLymphomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
April 13
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A MyLymphomaTeam Member

Joy, my lymphoma was diagnosed because I saw a neurologist about my neuropathy- soles of feet. He ran a lymphoma detection test. After that I saw an oncologist and chose 4 weekly infusions of Rituxan. All affected cells were eradicated by the third week. My foot neuropathy continues but is only there and mild. That’s my Marginal Zone L story.

April 14
MyLymphomaTeam

How common is peripheral neuropathy after Rituxan (rituximab) infusions for lymphoma?

Peripheral neuropathy isn't typically listed as a common side effect of Rituxan itself. The chemotherapy drugs used alongside Rituxan are more often the culprits.

Chemotherapy-induced peripheral neuropathy (CIPN) develops in 30 percent Show Full Answer

How common is peripheral neuropathy after Rituxan (rituximab) infusions for lymphoma?

Peripheral neuropathy isn't typically listed as a common side effect of Rituxan itself. The chemotherapy drugs used alongside Rituxan are more often the culprits.

Chemotherapy-induced peripheral neuropathy (CIPN) develops in 30 percent to 40 percent of people who undergo cancer treatment. The drugs most likely to cause nerve damage include:

* Vincristine (formerly Oncovin)
* Brentuximab vedotin (Adcetris)
* Bortezomib (Velcade)
* Platinum-based drugs like cisplatin and carboplatin

If you're receiving R-CHOP (which combines Rituxan with chemotherapy including vincristine), the neuropathy would more likely come from the vincristine component rather than the Rituxan.

Many people find that neuropathy symptoms improve or resolve after treatment ends, though sometimes symptoms can linger. If you're experiencing numbness, tingling, or pain, let your doctor know so they can monitor your symptoms and help manage them.

April 13

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