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Real members of MyLymphomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

I have found two problems with Rituxin following chemo for Follicular Lymphoma treatment. I seem to be gaining weight.

A MyLymphomaTeam Member asked a question 💭
Mount Dora, FL

I am following a weight loss plan almost 100% of the time. And exercise is very hard since I seem to have intense pain, numbness, and muscle spasms (maybe even a tendonitis) in my right calf, right foot, and my hands. I recently bought a cane to assist. Has this happened to anyone else?

April 18
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Reactions
A MyLymphomaTeam Member

LindaMullaney,
Hi and welcome to the site. Everyone here is so friendly and helpful. I have/had DLBCL and had treatments of rchop chemo. I’ve been in remission for 5 yrs. I was diagnosed with PMR after treatments and had to be on steroids for a year. I gained 50lbs. Still have only lost about 20lbs. But I’m blessed to be alive. I hope you feel better soon. Kelly

April 18
MyLymphomaTeam

Are weight gain and pain/numbness common side effects of rituximab and chemotherapy for follicular lymphoma?

Yes, other MyLymphomaTeam members have experienced similar challenges. Weight gain can occur as a side effect of lymphoma treatment, even when following a weight loss plan carefully.

The pain, numbness, and muscle Show Full Answer

Are weight gain and pain/numbness common side effects of rituximab and chemotherapy for follicular lymphoma?

Yes, other MyLymphomaTeam members have experienced similar challenges. Weight gain can occur as a side effect of lymphoma treatment, even when following a weight loss plan carefully.

The pain, numbness, and muscle spasms you're describing sound like they could be related to peripheral neuropathy, which is a known side effect of chemotherapy. This condition causes numbness, tingling, or pain in the hands and feet, and can make exercise very difficult.

What members have shared:

A MyLymphomaTeam member noted: "I have joint pain most days of the week." Another shared: "I am finding that because I am anemic, the exercise really wiped me out."

Important considerations:

Your symptoms warrant a conversation with your healthcare team, especially since they're affecting your mobility and quality of life. They may be able to:

- Adjust medications or dosages
- Check for anemia, which can worsen fatigue and exercise tolerance
- Provide guidance on safe, modified exercises
- Refer you to a physical therapist who can work with your specific limitations

Using a cane is a smart adaptation. Continue being cautious with exercise, especially given the numbness and balance concerns, to reduce fall risk.

April 18

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