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Real members of MyLymphomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyLymphomaTeam Member asked a question 💭
Anglesey Uk

I was diagnosed with a low grade NH Lymphoma in December 2024, have had 6 x RChop and now on Rituximab and Lenalidomide immunotherapy.

May 17
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MyLymphomaTeam

What a journey you've been on since December — completing 6 rounds of R-CHOP and now navigating a new treatment phase takes real strength.

Palpitations and heart-related changes are worth taking seriously during lymphoma treatment. Both R-CHOP and lenalidomide can affect the cardiovascular system, and heart rhythm changes Show Full Answer

What a journey you've been on since December — completing 6 rounds of R-CHOP and now navigating a new treatment phase takes real strength.

Palpitations and heart-related changes are worth taking seriously during lymphoma treatment. Both R-CHOP and lenalidomide can affect the cardiovascular system, and heart rhythm changes like atrial fibrillation have been reported with these therapies. Lenalidomide in particular carries a known increased risk of blood clots, which can sometimes contribute to heart rhythm issues. Key things to watch for include:

- Heart palpitations or irregular heartbeat
- Shortness of breath
- Chest discomfort
- Swollen limbs
- Unusual fatigue

It's really important to report these symptoms to your oncology team promptly — don't wait for your next scheduled appointment if symptoms feel new or are worsening.

Other MyLymphomaTeam members have shared similar concerns about heart-related side effects during treatment, so you're definitely not alone in experiencing this.

May 17

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