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I was diagnosed with NHL High Grade B-Cell lymphoma not otherwise specified that was located in my right testicle. What is survival rate?

A MyLymphomaTeam Member asked a question 💭
Anchorage, AK

RIGHT TESTIS, ORCHIECTOMY
– High grade B-cell lymphoma, CD20 positive, compatible with HGBCL- NOS (see comment)
– Lymphoma forms a 12.6 cm mass and involves the spermatic cord margin
COMMENT
The mass demonstrates a uniform histologic pattern of small to intermediate sized
lymphocytes with scant cytoplasm, dense nuclei and mitotic activity diffusely infiltrating the
testicle. Histologic features of DLBCL or plasma cell differentiation are not identified. These
features are of an aggressive B… read more

July 3
 · 
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B-Cell Lymphoma Survival Rates and Prognosis Read Article...
MyLymphomaTeam

First, it's worth acknowledging that receiving a diagnosis like this and reading through pathology reports is a lot to process — and it makes complete sense to want to understand what the numbers mean for your situation.

For primary testicular lymphoma (PTL) overall, survival rates vary significantly based on the stage at Show Full Answer

First, it's worth acknowledging that receiving a diagnosis like this and reading through pathology reports is a lot to process — and it makes complete sense to want to understand what the numbers mean for your situation.

For primary testicular lymphoma (PTL) overall, survival rates vary significantly based on the stage at diagnosis:

- Early-stage PTL has a five-year survival rate of up to 76% with treatment
- Advanced-stage PTL has a five-year survival rate of around 47% with treatment Your specific case has some details worth discussing with your oncologist, as several factors can influence prognosis. Based on what's in your pathology report:

- The tumor is large (12.6 cm), which is considered a factor that can affect outlook
- The lymphoma involves the spermatic cord margin, suggesting it may have spread beyond the testicle itself
- A Ki-67 of ~80% indicates the cancer cells are dividing rapidly, which signals an aggressive lymphoma
- The CD20-positive finding is actually important — it means treatments like rituximab (Rituxan) may be effective for you

The good news is that being CD20 positive opens the door to targeted therapies. Your oncologist will use all of these details together — along with staging results — to build the most effective treatment plan for your specific situation.

These numbers are population-level statistics and don't define your individual outcome. Please make sure to have a detailed conversation with your oncologist about what these findings mean specifically for you.

July 3

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