What does a hypodense lesion on the spleen mean for someone with MCL in remission and on Calquence and Venetoclax?
A hypodense lesion on the spleen simply means an area that appears darker than surrounding tissue on a CT scan. It's understandably worrying to see this after things were going well — but it's important to know Show Full Answer
What does a hypodense lesion on the spleen mean for someone with MCL in remission and on Calquence and Venetoclax?
A hypodense lesion on the spleen simply means an area that appears darker than surrounding tissue on a CT scan. It's understandably worrying to see this after things were going well — but it's important to know that not all lesions mean the cancer is active again.
Your oncologist will likely want to investigate further to determine what the lesion is. It could be related to MCL, or it could be something benign like a cyst. Since you're in your second remission and currently on Calquence (acalabrutinib) and Venetoclax, your care team is already using targeted therapies known to be effective for MCL. These are among the recommended options for managing MCL, especially after relapse.
Some important steps to consider right now:
- Contact your oncologist promptly to discuss what the lesion means in your specific situation
- Ask whether additional imaging (like a PET scan) or a biopsy might be needed to get a clearer picture
- Keep track of any new symptoms, such as abdominal pain, bloating, or swelling, and report them immediately
- Ask about your current treatment plan — whether any adjustments might be needed based on this finding
You're not alone in navigating unexpected scan results during remission. Other MyLymphomaTeam members have shared similar experiences of scans revealing unexpected findings while on targeted therapies. Staying closely connected with your care team is the most important thing right now.
7 days ago
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