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A MyLymphomaTeam Member asked a question 💭
Bangalore India
March 4, 2025
 · 
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A MyLymphomaTeam Member

The Red Devil , Rituximab and bendeka.

March 5, 2025
A MyLymphomaTeam Member

MuthuswamyChandrashekar,
I had 6 treatments, one every 3 weeks. The first week was a bit rough . Second and third week better, then had to have another treatment. Made sure I stayed hydrated all the time. Drank lots of water even through the infusion. The infusion nurses are angels in disguise and are a wealth of information. I also tried to eat protein for my blood I was told. I didn't have Etoposide. I had RCHOP only. I of course lost my hair but it will come back. When I lost my hair I figured the chemo was working killing the cancer. But everyone is different in how rchop effects them. I've been in remission for 4 yrs. God and RCHOP saved my life. I'm here for you if you have any other questions. I hope you are having a relaxing day. Kelly

March 4, 2025
A MyLymphomaTeam Member

MuthuswamyChandrashekhar,
Hi and welcome to the site. Everyone on here is so nice, helpful and supportive. I too have/had DLBCL stage IV and T cell rich too. You're the first one that I've met with the exact same diagnosis. I had 6 treatments of RCHOP chemo. I've been in remission for 4 yrs. If you have any questions for me please do not hesitate to ask. Kelly

March 4, 2025
A MyLymphomaTeam Member

Thank You Kelly....how was your journey during R-CHOP treatment ? Was Etoposide given along with R-CHOP ?

March 4, 2025
MyLymphomaTeam

The standard first-line treatment for Stage IV B-cell lymphoma typically involves R-CHOP, which combines rituximab (Rituxan) with a chemotherapy regimen including cyclophosphamide, doxorubicin, vincristine, and prednisone. This combination therapy has shown significant effectiveness in treating aggressive B-cell lymphomas Show Full Answer

The standard first-line treatment for Stage IV B-cell lymphoma typically involves R-CHOP, which combines rituximab (Rituxan) with a chemotherapy regimen including cyclophosphamide, doxorubicin, vincristine, and prednisone. This combination therapy has shown significant effectiveness in treating aggressive B-cell lymphomas. If the initial treatment isn't effective or if the lymphoma returns, several second-line treatment options are available that have shown promising results:

- CAR T-Cell Therapy (including options like Yescarta, Breyanzi, or Kymriah)
- Bispecific antibody treatments (such as Epkinly)
- Pola-R-CHP combination chemotherapy
- Bone marrow transplant combined with high-dose chemotherapy

These newer treatment approaches have been showing significant improvements in both event-free survival and overall survival rates.

March 4, 2025

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