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Denver, NC
May 21, 2025
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Primary breast lymphoma (PBL) symptoms typically include
- A painless breast lump
- Swollen lymph nodes, usually in the armpit on the same side as the tumor
- Breast pain
- Unexplained fever
- Unexplained weight loss
- Night sweats that drench clothing
- Fatigue
- Itchy skin with possible rash
- Loss of appetite Treatment Show Full Answer

Primary breast lymphoma (PBL) symptoms typically include:
- A painless breast lump
- Swollen lymph nodes, usually in the armpit on the same side as the tumor
- Breast pain
- Unexplained fever
- Unexplained weight loss
- Night sweats that drench clothing
- Fatigue
- Itchy skin with possible rash
- Loss of appetite Treatment options for PBL typically include:
- Combination of localized radiation therapy
- Systemic chemotherapy
- Targeted drug therapy like rituximab
- External beam radiation therapy, which is delivered in an outpatient setting

Common chemotherapy combinations may include R-CHOP (which includes rituximab) or other regimens depending on the specific type and stage of lymphoma. Your care team can help manage treatment side effects like nausea, fatigue, and decreased immune function.

May 21, 2025

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