Have you or others completed CAR T-cell therapy for large B-cell lymphoma?
CAR T-cell therapy has been used successfully for many people with large B-cell lymphoma, particularly when other treatments haven't worked. There are three FDA-approved options available:
- Axicabtagene ciloleucel (Yescarta)
- Lisocabtagene Show Full Answer
Have you or others completed CAR T-cell therapy for large B-cell lymphoma?
CAR T-cell therapy has been used successfully for many people with large B-cell lymphoma, particularly when other treatments haven't worked. There are three FDA-approved options available:
- Axicabtagene ciloleucel (Yescarta)
- Lisocabtagene maraleucel (Breyanzi)
- Tisagenlecleucel (Kymriah)
These therapies have shown strong results in both clinical trials and real-world use, even for people with advanced disease or those who are older.
One of the biggest benefits is that CAR T cells can keep working after the infusion, sometimes for weeks or months. Many people have achieved long-lasting remissions, even when multiple other treatments had stopped working.
The process involves collecting your T cells, modifying them in a lab to recognize and attack lymphoma cells, then infusing them back into your body. You'll receive a short course of low-dose chemotherapy before the infusion.
Potential side effects can include fever, low blood pressure, confusion, or in rare cases, more serious immune-related effects. Your healthcare team will monitor you closely to catch and manage these early.
Many MyLymphomaTeam members have shared their experiences with CAR T-cell therapy, so connecting with others who've been through it might provide helpful insights as you prepare for treatment.
March 5
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