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March 12
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Has anyone experienced high alkaline phosphatase levels after finishing chemo and immunotherapy for DLBCL?

High alkaline phosphatase levels after treatment can be concerning, but they don't automatically mean a relapse. While elevated levels can sometimes indicate lymphoma activity in the liver or bones, many other factors Show Full Answer

Has anyone experienced high alkaline phosphatase levels after finishing chemo and immunotherapy for DLBCL?

High alkaline phosphatase levels after treatment can be concerning, but they don't automatically mean a relapse. While elevated levels can sometimes indicate lymphoma activity in the liver or bones, many other factors can cause this lab result to be high.

If you're experiencing symptoms alongside the elevated levels, it's important to watch for signs of potential relapse, including:

* Swollen or enlarged lymph nodes
* B symptoms (night sweats, fever, unexplained weight loss of at least 10% of body weight)
* Loss of appetite or feeling full quickly
* Abdominal pain or swelling

However, these symptoms can also be caused by other conditions unrelated to lymphoma relapse.

Your oncologist will likely want to do additional testing to determine the cause. This may include imaging tests, blood work, or possibly a biopsy to confirm whether your symptoms are due to a relapse or another condition.

The risk of DLBCL relapse is highest within the first two years after completing treatment, so regular follow-up appointments and monitoring are especially important during this time. If you're noticing any new or concerning symptoms, reach out to your oncology team right away rather than waiting for your next scheduled appointment.

March 12

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