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A MyLymphomaTeam Member asked a question 💭
New York, NY
May 22
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High alkaline phosphatase (ALP) isn't specifically listed as a primary early warning sign of DLBCL relapse, but it can sometimes be associated with liver or bone involvement when lymphoma returns. It's worth flagging to your oncologist if levels are elevated.

The more commonly recognized signs of DLBCL relapse to watch for Show Full Answer

High alkaline phosphatase (ALP) isn't specifically listed as a primary early warning sign of DLBCL relapse, but it can sometimes be associated with liver or bone involvement when lymphoma returns. It's worth flagging to your oncologist if levels are elevated.

The more commonly recognized signs of DLBCL relapse to watch for include:

- Swollen lymph nodes — painless lumps under the skin
- B symptoms — drenching night sweats, fever, and unexplained weight loss (10% or more of body weight over 6 months)
- Abdominal pain — which can signal swollen lymph nodes deeper in the body
- Loss of appetite — or feeling full very quickly when eating
- Fatigue A key blood marker that doctors do monitor closely for DLBCL relapse is LDH (lactate dehydrogenase). Higher LDH levels are linked to a worse outlook and can signal disease progression.

If you're concerned about your ALP levels or any new symptoms, reaching out to your oncology team sooner rather than later is always the right move. They can order the right tests to get a clearer picture of what's going on.

May 22

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