Has anyone experienced gastric lymphoma after being in remission from Hodgkin's lymphoma?
Yes, gastric lymphoma can develop, though it's quite rare. Primary gastric lymphoma makes up about 30-40% of extranodal lymphomas and accounts for roughly 5% of all stomach cancers. It's more common in adults over 50 and affects men Show Full Answer
Has anyone experienced gastric lymphoma after being in remission from Hodgkin's lymphoma?
Yes, gastric lymphoma can develop, though it's quite rare. Primary gastric lymphoma makes up about 30-40% of extranodal lymphomas and accounts for roughly 5% of all stomach cancers. It's more common in adults over 50 and affects men two to three times more often than women.
While gastric forms of Hodgkin lymphoma are extremely rare with only a few cases reported, most gastric lymphomas are non-Hodgkin lymphomas. The two main types are:
- Diffuse large B-cell lymphoma (DLBCL) - about 60% of cases, fast-growing
- MALT lymphoma - about 40% of cases, slow-growing
Less commonly, it can be mantle cell, follicular, or peripheral T-cell lymphoma. Treatment options depend on the specific type found in your biopsy results.
For MALT lymphoma, treatment often starts with antibiotics if H. pylori infection is present. If antibiotics don't work, options include radiation therapy, chemotherapy drugs like chlorambucil, or targeted therapies like zanubrutinib.
For DLBCL, more aggressive treatment is typically needed, usually the R-CHOP chemotherapy regimen (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone). Early-stage cases may receive radiation after chemo, while advanced cases usually receive chemo alone. Newer immunotherapies like CAR T-cell therapy may be options for advanced DLBCL.
If it's Hodgkin lymphoma, treatment typically involves systemic chemotherapy regimens like ABVD or brentuximab-based combinations.
Surgery is rarely needed and usually reserved for complications like bleeding or perforation. Prognosis varies significantly based on the type and stage. The specific subtype of gastric lymphoma greatly influences outlook and treatment success. Waiting for your biopsy and flow cytometry results will provide crucial information about your specific situation and help your medical team determine the best treatment approach.
April 3
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