Connect with others who understand.

  •   Learn from expert-reviewed resources
  •   Real advice from people who’ve been there
  •   People who understand what you’re going through
Sign Up Log In
All Resources Treatments A-Z Personal Assistant Help Center Crisis
Powered By
Real members of MyLymphomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

I have Stage 4 Marginal Zone Lymphoma and I’m supposed to start Rituximab infusions but just found out about a clinical trial.

A MyLymphomaTeam Member asked a question 💭
Many, LA

Has anyone heard of, had experience with any of these drugs or know any information that can help me. The drugs are Rituximab, Acalabrutinib, and Lenalidomide. I think it is 13 cycles. It is being offered to me through MD Anderson. Any info is appreciated. Have a blessed day!

April 21
 · 
Reactions
A MyLymphomaTeam Member

Thank you for the response. Sending good wishes your way.

May 1
A MyLymphomaTeam Member

I’m also just diagnosed with Stage 4 Follicular lymphoma & in a clinical trial. They will watch us for years. I feel like I have my own support team with it. Everyone is optimistic. Good luck with yours! I’m also with MD Anderson.

April 30
MyLymphomaTeam

Should you consider this clinical trial for your stage 4 marginal zone lymphoma?

It's wonderful that you're exploring all your options! Clinical trials can offer access to promising treatment combinations, especially for advanced-stage lymphoma.

About the drugs in this trial:

Rituximab is a monoclonal antibody that Show Full Answer

Should you consider this clinical trial for your stage 4 marginal zone lymphoma?

It's wonderful that you're exploring all your options! Clinical trials can offer access to promising treatment combinations, especially for advanced-stage lymphoma.

About the drugs in this trial:

Rituximab is a monoclonal antibody that targets B cells (the cancer cells in lymphoma). It's commonly used for marginal zone lymphoma and is less toxic than traditional chemotherapy.

Acalabrutinib is a BTK inhibitor that blocks a protein B cells need to grow and divide. It's typically used for relapsed or refractory marginal zone lymphoma but may be studied earlier in treatment through trials.

Lenalidomide is an immunotherapy drug that helps your immune system fight cancer cells.

Why this combination matters:

This trial appears to combine targeted therapies that work differently to attack lymphoma cells. Clinical trials often test whether combining drugs is more effective than standard treatment alone. Questions to ask your oncologist:

* How does this trial compare to standard rituximab treatment for my specific situation?
* What are the potential side effects of combining these three drugs?
* Will I receive close monitoring throughout the trial?
* What happens if the trial treatment doesn't work for me?

A MyLymphomaTeam member shared: "Clinical trials helped me when I was stage 4. I was so sick last year. I'm still sick, but much better."

Your oncologist at MD Anderson knows your case best and can help you weigh whether this trial is right for you. Wishing you clarity in your decision!

April 21

Related Questions

View All

Does anyone have cancer in their bone marrow?

A MyLymphomaTeam Member asked a question 💭
Lachine, QC
June 5, 2023

Anyone with splenic Marginal zone lymphoma

A MyLymphomaTeam Member asked a question 💭
New Jersey, NJ
March 31

Marginal Zone Lymphoma: An Overview
Splenic Marginal Zone Lymphoma: Prognosis, Symptoms, and More
Mantle Cell Lymphoma Stages: Are Most People Diagnosed at Stage 4?