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Is frequent diarohea common with mantle cell lymphoma some swelling of abdomen. This symptom has come about in the last 2-3 months .

A MyLymphomaTeam Member asked a question 💭
Australia

Diagnosed MCL with specialist thinking indolent however that was 6 months ago. Diagnosed in 2025 MCL with t11-t14 positive. No lymph nodes or spleen problems . 2 years prior to MCL lymphocytosis. Current new symptom alongside bone pain and sweats , diarrhoea is a purging type occurring in morning with cramps and swollen abdomen. Current diet lactose free diet very small meals and good quality diet.
Is this common
Mar2

June 14
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MyLymphomaTeam

These are really important symptoms to flag, and it's completely understandable to want to know if they're connected to MCL. The short answer is — yes, gastrointestinal symptoms like diarrhea, cramping, and abdominal swelling can be associated with MCL, particularly because MCL often develops in the gastrointestinal tract.

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These are really important symptoms to flag, and it's completely understandable to want to know if they're connected to MCL. The short answer is — yes, gastrointestinal symptoms like diarrhea, cramping, and abdominal swelling can be associated with MCL, particularly because MCL often develops in the gastrointestinal tract.

Common GI-related symptoms seen with MCL include:

- Diarrhea
- Abdominal pain and cramping
- Bloating or abdominal swelling
- Nausea or vomiting
- Indigestion What makes this particularly worth paying attention to is that these new symptoms — especially combined with bone pain and night sweats (which are classic "B symptoms") — could suggest the disease may be changing in behavior. An indolent MCL diagnosis from 6 months ago doesn't mean it stays that way, and new or worsening symptoms are always a signal worth investigating promptly.

Given the combination of:
- Purging-type morning diarrhea with cramps
- Abdominal swelling
- Bone pain
- Night sweats

...it would be strongly advisable to contact the oncology team as soon as possible rather than waiting for the next scheduled appointment. These symptoms together warrant reassessment, possibly including updated imaging or blood work, to check whether the MCL has progressed beyond its initial indolent presentation.

The dietary adjustments being made are sensible, but managing symptoms through diet alone won't address any underlying disease activity if that's what's driving these changes.

June 14

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