What types of lymphoma is CAR T-cell therapy suitable for?
CAR T-cell therapy is mainly used when lymphoma has relapsed (come back after treatment) or is refractory (hasn't responded to other treatments). It's approved for several specific lymphoma types.
Here are the FDA-approved CAR T-cell therapies and the lymphomas Show Full Answer
What types of lymphoma is CAR T-cell therapy suitable for?
CAR T-cell therapy is mainly used when lymphoma has relapsed (come back after treatment) or is refractory (hasn't responded to other treatments). It's approved for several specific lymphoma types.
Here are the FDA-approved CAR T-cell therapies and the lymphomas they treat:
- Axicabtagene ciloleucel (Yescarta) — Diffuse large B-cell lymphoma (DLBCL), high-grade B-cell lymphoma, primary mediastinal large B-cell lymphoma, follicular lymphoma
- Lisocabtagene maraleucel (Breyanzi) — Large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma
- Tisagenlecleucel (Kymriah) — Large B-cell lymphoma, relapsed or refractory follicular lymphoma
- Brexucabtagene autoleucel (Tecartus) — Mantle cell lymphoma
It's worth noting that CAR T-cell therapy is typically considered after at least two other treatments have been tried. A doctor can help determine whether it's a suitable option based on the specific lymphoma type and overall health.
July 19
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