Diffuse Large B-Cell Lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma, making up about one-third of all cases. It starts in B cells — white blood cells that normally help your immune system fight infections.
In DLBCL, these B cells become cancerous and grow out of control, crowding out healthy cells and Show Full Answer
Diffuse Large B-Cell Lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma, making up about one-third of all cases. It starts in B cells — white blood cells that normally help your immune system fight infections.
In DLBCL, these B cells become cancerous and grow out of control, crowding out healthy cells and building up in organs throughout the body. The word "diffuse" refers to how the cancer cells look under a microscope — they're spread out rather than clustered together. It's considered an aggressive (fast-growing) cancer, but here's the good news: it often responds well to treatment, and many people achieve complete remission.
DLBCL most commonly affects middle-aged and older adults, with an average diagnosis age of 64. DLBCL can develop in the lymph nodes or in other parts of the body, including:
- Intestines
- Stomach
- Kidneys
- Liver
- Bone marrow
- Skin
The most common treatment is a five-drug regimen called R-CHOP, though your doctor will tailor the approach based on your specific situation. Getting a second opinion is always a reasonable step to make sure everything is on the right track.
October 19
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