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Stage 4 follicular lymphoma with bone marrow involvement is advanced, and the disease can transform or progress over time. Transformation to a more aggressive lymphoma, such as diffuse large B-cell lymphoma (DLBCL), occurs in about 25% to 60% of cases. Progression rates vary, but advanced stages like stage 4 often require Show Full Answer

Stage 4 follicular lymphoma with bone marrow involvement is advanced, and the disease can transform or progress over time. Transformation to a more aggressive lymphoma, such as diffuse large B-cell lymphoma (DLBCL), occurs in about 25% to 60% of cases. Progression rates vary, but advanced stages like stage 4 often require ongoing treatment to manage the disease. Close monitoring and tailored care are crucial.

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