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While R-CHOP is effective for many people with DLBCL, about 30-40% of patients may not respond well to this treatment. This can happen in two ways: either the cancer is refractory (meaning most cancer cells cannot be destroyed by the treatment) or the cancer relapses (responds initially but then returns). Alternative Show Full Answer

While R-CHOP is effective for many people with DLBCL, about 30-40% of patients may not respond well to this treatment. This can happen in two ways: either the cancer is refractory (meaning most cancer cells cannot be destroyed by the treatment) or the cancer relapses (responds initially but then returns). Alternative treatment options exist for those who cannot use R-CHOP. For example, R-EPOCH, which includes all the R-CHOP medications plus etoposide, may be recommended as a more aggressive therapy option. Additionally, R-miniCHOP, which uses lower doses of the same medications, might be suitable for those who cannot tolerate standard R-CHOP doses. It's important to discuss specific alternative treatment options with your healthcare team. They can review your medical history and help determine the most appropriate next steps based on your individual situation.

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5 Facts About R-CHOP Chemo for DLBCL and What To Expect