DLBCL (Diffuse Large B-cell Lymphoma) is a blood cancer affecting B cells, which are white blood cells that normally help fight infections. It's a fast-growing but typically treatable form of non-Hodgkin lymphoma that usually affects middle-aged and older adults, with an average diagnosis age of 64.
Common symptoms Show Full Answer
DLBCL (Diffuse Large B-cell Lymphoma) is a blood cancer affecting B cells, which are white blood cells that normally help fight infections. It's a fast-growing but typically treatable form of non-Hodgkin lymphoma that usually affects middle-aged and older adults, with an average diagnosis age of 64.
Common symptoms include:
• Swollen lymph nodes in neck, armpits, or groin
• Fever above 103°F lasting 2+ days
• Drenching night sweats
• Unexplained weight loss (10%+ in 6 months)
• Possible abdominal pain or diarrhea if affecting stomach/intestines Diagnosis typically involves:
• Medical history review
• Physical examination
• Lymph node biopsy
• Additional specialized testing
Treatment varies by stage:
• Stages 1-2: Chemotherapy or chemoimmunotherapy, possibly followed by radiation
• Stages 3-4: More intensive chemoimmunotherapy cycles, with radiation in specific cases
Many people achieve complete remission after treatment, though prognosis depends on cancer stage and individual health factors.
June 9, 2025