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A MyLymphomaTeam Member asked a question 💭
Palm Coast, FL
August 23, 2025
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Answer Summary

Members discussed whether Rituxan treatment can worsen peripheral neuropathy, with one member sharing that her husband could hardly walk after... Read more

Members discussed whether Rituxan treatment can worsen peripheral neuropathy, with one member sharing that her husband could hardly walk after treatment, while another experienced severe whole-body numbness, tingling, and exhaustion requiring a walker. Several members offered practical suggestions including checking B12 and magnesium levels (which brought immediate improvement for one person), trying topical Frankincense and Myrrh oil, taking vitamin B1 or Benfotiamine (a more absorbable form), and contacting lymphoma nurses directly for faster medical guidance rather than waiting weeks for a primary care appointment. A recurring theme was the frustration of long wait times for appointments when experiencing urgent symptoms, contrasted with appreciation for faster-track systems and emergency nurse hotlines available in some healthcare settings.

A MyLymphomaTeam Member

I have 2 pcp(primary care Docs.) My main one is in Palm Coast Florida where our primary residence is. My next appointment with him is November 12th. I have a second one for the other 5 or so months of the year that we just are seeing for the first time on October 8th. The reason for this is we spend those months in Western North Carolina (Hendersonville) in the Mountains. It is just too hot in Florida in the summer. Our Log home in North Carolina is an inheritance from my Mom. She passed last May at the age of 95. So we are exceptionally lucky to have the best of both worlds. My oncologist is here in Hendersonville NC because this is where the lymphoma was diagnosed. I do have a Hematologist/Oncologist in Palm Coast Florida that I was seeing for a seperate health issue. We are able to continue with him to include the lymphoma monitoring. It’s actually very convenient because all of the docs are in the same health organization in both states and can share all my information via the computer system which is the same. Long story but it’s the best way to explain it. 😀

August 26, 2025
A MyLymphomaTeam Member

Hi Joy….You may want to have your B12 and Magnesium levels in your blood checked. Low levels of either of these can contribute to neuropathy symptoms. I got treatment for both and saw immediate improvement. Can’t hurt to ask.

August 25, 2025
A MyLymphomaTeam Member

So sorry..sounds extremely painful and disabling..did this happen because of rituxan for you Joy? Frankincense and Myrrah oil blend helps to some extent by topical application . Sending love and hugs

August 23, 2025
MyLymphomaTeam

While Rituxan (rituximab) itself is not typically associated with causing peripheral neuropathy, it's important to understand that many lymphoma treatments can affect nerve function. Peripheral neuropathy is a common side effect of lymphoma treatment that can cause numbness, tingling, weakness, or pain in hands, feet, and Show Full Answer

While Rituxan (rituximab) itself is not typically associated with causing peripheral neuropathy, it's important to understand that many lymphoma treatments can affect nerve function. Peripheral neuropathy is a common side effect of lymphoma treatment that can cause numbness, tingling, weakness, or pain in hands, feet, and legs. The most common causes of chemotherapy-induced peripheral neuropathy (CIPN) in lymphoma treatment are specific drugs like:

• Brentuximab vedotin (Adcetris)
• Vincristine (formerly Oncovin)
• Bortezomib (Velcade)
• Platinum-based drugs like cisplatin and carboplatin

About 30-40% of people undergoing cancer treatment develop CIPN. While symptoms often improve after treatment ends, some people may experience longer-lasting effects.

August 23, 2025
A MyLymphomaTeam Member

This is true. Actually I have found that Benfotiamine works even better and faster. it is a synthetic derivative of Thiamine that is more readily absorbed by the body. I have used it for several years with no side effects.

October 4, 2025

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