Could knee pain and swelling two months after treatment be lymphoma?
It's understandable to be concerned about new symptoms after treatment. While your bone biopsy was negative for B cells post-treatment, new symptoms always warrant medical attention.
The knee pain, swelling, and bone infarcts shown on your MRI could have Show Full Answer
Could knee pain and swelling two months after treatment be lymphoma?
It's understandable to be concerned about new symptoms after treatment. While your bone biopsy was negative for B cells post-treatment, new symptoms always warrant medical attention.
The knee pain, swelling, and bone infarcts shown on your MRI could have several causes:
- Treatment side effects: Chemotherapy can cause bone pain that persists long after treatment ends. Some MyLymphomaTeam members report bone pain continuing for months or even years after finishing chemo.
- Bone damage from treatment: Chemotherapy and other cancer treatments can damage healthy cells alongside cancerous ones, potentially affecting bones and joints.
- Relapsed or refractory disease: DLBCL can sometimes relapse after treatment or be refractory (resistant to treatment), though your negative bone biopsy is encouraging.
What you should do:
Your oncologist needs to evaluate these symptoms promptly. They may recommend additional tests to determine if this represents lymphoma recurrence or another cause. Don't hesitate to contact your care team right away—new swelling and pain deserve immediate attention, especially within the first few months after treatment.
Many members experience ongoing bone pain after treatment that isn't related to active lymphoma, but only your medical team can determine what's causing your specific symptoms.
November 7, 2025
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