... One class of drugs, known as proteasome inhibitors, includes the drug Velcade (bortezomib). Proteasome inhibitors prevent the destruction of proteins that slow cell division, which helps to control the growth of the cancer.The drug Imbruvica (ibrutinib) is also used to treat WM, either alone or in combination with rituximab. ...
    
   
  
    Waldenstrom’s Macroglobulinemia: Treatment Options
    
      ... One class of drugs, known as proteasome inhibitors, includes the drug Velcade (bortezomib). Proteasome inhibitors prevent the destruction of proteins that slow cell division, which helps to control the growth of the cancer.The drug Imbruvica (ibrutinib) is also used to treat WM, either alone or in combination with rituximab. ...
     
    
   
 
      
  
  
  
    ... high-dose cytarabine, and cisplatin A combination of rituximab and bendamustine (Bendeka, Treanda) may be used to treat people who can’t tolerate intense chemotherapy treatments, including older individuals with MCL or those who have other health conditions.Targeted therapies that specifically block proteins involved in MCL include bortezomib (Boruzu, Velcade ...
    
   
  
    Mantle Cell Lymphoma Stages: Are Most People Diagnosed at Stage 4?
    
      ... high-dose cytarabine, and cisplatin A combination of rituximab and bendamustine (Bendeka, Treanda) may be used to treat people who can’t tolerate intense chemotherapy treatments, including older individuals with MCL or those who have other health conditions.Targeted therapies that specifically block proteins involved in MCL include bortezomib (Boruzu, Velcade ...
     
    
   
 
      
  
  
  
    ... Examples of MCL treatments include: First-line (initial) treatment with R-CHOP — Rituximab (Rituxan), cyclophosphamide (Cytoxan), hydroxydaunorubicin (also known as doxorubicin, Adriamycin), vincristine (Onvocin), and prednisone Hyper-CVAD — Cyclophosphamide, vincristine, doxorubicin, dexamethasone Bendamustine (Treanda) Bortezomib (Velcade) Lenalidomide ...
    
   
  
    Mantle Cell Lymphoma Prognosis: What Is the Survival Rate
    
      ... Examples of MCL treatments include: First-line (initial) treatment with R-CHOP — Rituximab (Rituxan), cyclophosphamide (Cytoxan), hydroxydaunorubicin (also known as doxorubicin, Adriamycin), vincristine (Onvocin), and prednisone Hyper-CVAD — Cyclophosphamide, vincristine, doxorubicin, dexamethasone Bendamustine (Treanda) Bortezomib (Velcade) Lenalidomide ...
     
    
   
 
      
  
  
  
    ... Velcade (bortezomib) is a type of targeted drug known as a proteasome inhibitor and is used as a treatment for MCL, either alone or in combination with chemotherapy and rituximab.Stem Cell TransplantA stem cell transplant, also called a bone marrow transplant, involves replacing the bone marrow of a person receiving treatment, which allows their body ...
    
   
  
    Understanding Mantle Cell Lymphoma
    
      ... Velcade (bortezomib) is a type of targeted drug known as a proteasome inhibitor and is used as a treatment for MCL, either alone or in combination with chemotherapy and rituximab.Stem Cell TransplantA stem cell transplant, also called a bone marrow transplant, involves replacing the bone marrow of a person receiving treatment, which allows their body ...
     
    
   
 
      
  
  
  
    ... Some of the chemotherapy drugs most likely to cause CIPN include: Brentuximab vedotin (Adcetris) Vincristine (formerly sold as Oncovin) bortezomib (Velcade) Platinum-based drugs like cisplatin (Platinol) and carboplatin (Paraplatin) CIPN develops in 30 percent to 40 percent of people who undergo cancer treatment. ...
    
   
  
    Peripheral Neuropathy and Lymphoma: Your Guide
    
      ... Some of the chemotherapy drugs most likely to cause CIPN include: Brentuximab vedotin (Adcetris) Vincristine (formerly sold as Oncovin) bortezomib (Velcade) Platinum-based drugs like cisplatin (Platinol) and carboplatin (Paraplatin) CIPN develops in 30 percent to 40 percent of people who undergo cancer treatment. ...
     
    
   
 
      
  
  
  
    ... Several existing drugs are already being explored as possible treatments for ATLL, including Velcade (bortezomib) and Treanda (bendamustine), which are currently approved to treat other forms of non-Hodgkin lymphoma. Another drug, Poteligeo (mogamulizumab), is a monoclonal antibody drug, meaning it can specifically recognize certain cell types. ...
    
   
  
    Adult T-Cell Leukemia/Lymphoma (ATLL): Your Guide
    
      ... Several existing drugs are already being explored as possible treatments for ATLL, including Velcade (bortezomib) and Treanda (bendamustine), which are currently approved to treat other forms of non-Hodgkin lymphoma. Another drug, Poteligeo (mogamulizumab), is a monoclonal antibody drug, meaning it can specifically recognize certain cell types. ...
     
    
   
 
      
  
  
  
    ... Bortezomib (Velcade) is a proteasome inhibitor used to treat certain forms of NHL such as mantle cell lymphoma.Bruton’s Tyrosine Kinase InhibitorsBruton’s tyrosine kinase (BTK) inhibitors block BTK, which is a protein that B cells need to survive. ...
    
   
  
    Non-Hodgkin Lymphoma Treatment: What You Need To Know
    
      ... Bortezomib (Velcade) is a proteasome inhibitor used to treat certain forms of NHL such as mantle cell lymphoma.Bruton’s Tyrosine Kinase InhibitorsBruton’s tyrosine kinase (BTK) inhibitors block BTK, which is a protein that B cells need to survive. ...
     
    
   
 
      
  
  
  
    ... For example, doctors have treated PBL with the myeloma-fighting drugs bortezomib (Velcade) and lenalidomide (Revlimid). Doctors may recommend using these drugs along with chemotherapy. Antiretroviral DrugsAntiretroviral therapy (ART) drugs help keep HIV under control. HIV-positive people with PBL often take ART as part of their treatment. ...
    
   
  
    What You Need To Know About Plasmablastic Lymphoma: Symptoms, Treatment, and Prognosis
    
      ... For example, doctors have treated PBL with the myeloma-fighting drugs bortezomib (Velcade) and lenalidomide (Revlimid). Doctors may recommend using these drugs along with chemotherapy. Antiretroviral DrugsAntiretroviral therapy (ART) drugs help keep HIV under control. HIV-positive people with PBL often take ART as part of their treatment. ...
     
    
   
 
      
  
  
  
    ... Bortezomib (Velcade) and ibrutinib (Imbruvica) — both targeted drugs that are approved to treat other forms of non-Hodgkin lymphoma — are being evaluated as potential treatment options for THL. Also under investigation is a new type of therapy called chimeric antigen receptor T-cell therapy, or CAR T-cell therapy. ...
    
   
  
    Triple-Hit Lymphoma: Your Guide
    
      ... Bortezomib (Velcade) and ibrutinib (Imbruvica) — both targeted drugs that are approved to treat other forms of non-Hodgkin lymphoma — are being evaluated as potential treatment options for THL. Also under investigation is a new type of therapy called chimeric antigen receptor T-cell therapy, or CAR T-cell therapy. ...
     
    
   
 
      
  
  
  
    ... Lenalidomide (Revlimid) is an oral immunotherapy that’s FDA-approved to treat relapsed or refractory MCL after at least two other treatments have been tried, one of which should be bortezomib (Velcade). ...