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Real members of MyLymphomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
June 30
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MyLymphomaTeam

Dealing with both DLBCL and Primary CNS Lymphoma at the same time is a lot to carry — you're definitely not alone in this, even if it can feel that way sometimes.

Many MyLymphomaTeam members have shared similar experiences with CNS lymphoma and methotrexate treatment. High-dose methotrexate is actually the standard Show Full Answer

Dealing with both DLBCL and Primary CNS Lymphoma at the same time is a lot to carry — you're definitely not alone in this, even if it can feel that way sometimes.

Many MyLymphomaTeam members have shared similar experiences with CNS lymphoma and methotrexate treatment. High-dose methotrexate is actually the standard first-line chemotherapy for CNS lymphoma, so your treatment path is very much in line with what others have gone through. Beyond methotrexate, doctors often combine it with other treatments. Common options used alongside or after methotrexate include:

- Rituximab (Rituxan)
- Cytarabine
- Vincristine (Oncovin)
- Ibrutinib (Imbruvica)
- Thiotepa (Tepadina)
- Temozolomide (Temodar)
- Whole brain radiation therapy
- Stem cell transplantation

It's worth having an open conversation with your care team about what comes next, especially regarding whether additional treatments or clinical trials might be right for your situation.

June 30

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