R-CHOP is a combination treatment that brings together chemotherapy and immunotherapy drugs to fight diffuse large B-cell lymphoma (DLBCL). It's considered the standard first-line treatment, meaning it's typically the first option doctors turn to after a diagnosis.
The name R-CHOP is actually an acronym made up of the Show Full Answer
R-CHOP is a combination treatment that brings together chemotherapy and immunotherapy drugs to fight diffuse large B-cell lymphoma (DLBCL). It's considered the standard first-line treatment, meaning it's typically the first option doctors turn to after a diagnosis.
The name R-CHOP is actually an acronym made up of the first letters of each drug in the combination:
- R — Rituximab (Rituxan), an immunotherapy drug that helps the immune system find and attack lymphoma cells
- C — Cyclophosphamide, a chemotherapy drug that damages cancer cell DNA
- H — Doxorubicin (also called hydroxydaunorubicin), a chemo drug that helps kill cancer cells
- O — Vincristine (formerly sold as Oncovin), a chemo drug that interferes with cancer cell growth
- P — Prednisone, a steroid that reduces inflammation and helps kill cancer cells Treatment is typically given in cycles — usually six cycles total, with each cycle lasting 21 days. Most of the drugs are given through an IV, while prednisone is taken as a pill for five days each cycle.
R-CHOP is effective for many people, with studies showing it can cure around 60–70% of newly diagnosed DLBCL cases. That said, it doesn't work for everyone, and your doctor will tailor the approach based on your specific situation.
July 31
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