PLANT ALKALOID/TOPOISOMERASE II INHIBITORS
VP-16, also known by its drug name, Etoposide, is a prescription medication used to treat several types of cancer including Hodgkin lymphoma and non-Hodgkin lymphoma. VP-16 is sometimes combined with other drugs such as Blenoxane, Cytoxan, Oncovin, and corticosteroids in a chemotherapy regimen to treat lymphoma.
VP-16 is an anticancer drug used in chemotherapy. VP-16 is a member of a class of drugs called plant alkaloids. VP-16 is also a topoisomerase II inhibitor. VP-16 is believed to work by preventing the replication of cancer cells.
How do I take it?
VP-16 is taken orally as a tablet or administered as an intravenous infusion during chemotherapy treatment.
The FDA-approved label for VP-16 lists common side effects including hair loss, mouth sores, nausea, vomiting, diarrhea, loss of appetite, low blood pressure, early menopause in women, and loss of fertility in men or women.
Rare but serious side effects listed for VP-16 include fetal harm in pregnant women and increased risk for developing other cancers.
For more details about this treatment, visit:
Etoposide – Chemocare
Lymphoma - Hodgkin: Treatment Options – Cancer.net
Treatment for Aggressive NHL Subtyps – Leukemia & Lymphoma Society
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